Importance of angina in patients with coronary disease, heart failure, and left ventricular systolic dysfunction: insights from STICH.

ABSTRACT:

Background

Patients with left ventricular (LV) systolic dysfunction, coronary artery disease (CAD), and angina are often thought to have a worse prognosis and a greater prognostic benefit from coronary artery bypass graft (CABG) surgery than those without angina.

Objectives

This study investigated: 1) whether angina was associated with a worse prognosis; 2) whether angina identified patients who had a greater survival benefit from CABG; and 3) whether CABG improved angina in patients with LV systolic dysfunction and CAD.

Methods

We performed an analysis of the STICH (Surgical Treatment for Ischemic Heart Failure) trial, in which 1,212 patients with an ejection fraction ≤35% and CAD were randomized to CABG or medical therapy. Multivariable Cox and logistic models were

SUBMITTER: Jolicœur EM 

PROVIDER: S-EPMC4655599 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature