Gut Colonization of Healthy Children and Their Mothers With Pathogenic Ciprofloxacin-Resistant Escherichia coli.

ABSTRACT:

Background

The reservoir of pathogenic ciprofloxacin-resistant Escherichia coli remains unknown.

Methods

We conducted a prospective cohort study of 80 healthy twins and their mothers to determine the frequency of excretion of ciprofloxacin-resistant, potentially pathogenic E. coli. Stool specimens were cultured selectively for ciprofloxacin-resistant gram-negative bacteria. Isolates were categorized on the basis of additional resistance and virulence profiles. We also prospectively collected clinical metadata.

Results

Fifteen children (19%) and 8 mothers (20%) excreted ciprofloxacin-resistant E. coli at least once. Overall, 33% of 40 families had at least 1 member whose stool specimen yielded ciprofloxacin-resistant E. coli on culture. Fifty-seven submitted stool spec

SUBMITTER: Gurnee EA 

PROVIDER: S-EPMC4655851 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature