Attenuation of reflected waves in man during retrograde propagation from femoral artery to proximal aorta.

ABSTRACT:

Background

Wave reflection may be an important influence on blood pressure, but the extent to which reflections undergo attenuation during retrograde propagation has not been studied. We quantified retrograde transmission of a reflected wave created by occlusion of the left femoral artery in man.

Methods

20 subjects (age 31-83 years; 14 male) underwent invasive measurement of pressure and flow velocity with a sensor-tipped intra-arterial wire at multiple locations distal to the proximal aorta before, during and following occlusion of the left femoral artery by thigh cuff inflation. A numerical model of the circulation was also used to predict reflected wave transmission. Wave reflection was measured as the ratio of backward to forward wave energy (WRI) and the ratio of peak

SUBMITTER: Baksi AJ 

PROVIDER: S-EPMC4657155 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature