Flupyradifurone: a brief profile of a new butenolide insecticide.

ABSTRACT:

Background

The development and commercialisation of new chemical classes of insecticides for efficient crop protection measures against destructive invertebrate pests is of utmost importance to overcome resistance issues and to secure sustainable crop yields. Flupyradifurone introduced here is the first representative of the novel butenolide class of insecticides active against various sucking pests and showing an excellent safety profile.

Results

The discovery of flupyradifurone was inspired by the butenolide scaffold in naturally occurring stemofoline. Flupyradifurone acts reversibly as an agonist on insect nicotinic acetylcholine receptors but is structurally different from known agonists, as shown by chemical similarity analysis. It shows a fast action on a broad range o

SUBMITTER: Nauen R 

PROVIDER: S-EPMC4657471 | biostudies-literature | 2015 Jun

REPOSITORIES: biostudies-literature