Clinical Relevance of Biomarkers of Oxidative Stress.

ABSTRACT:

Significance

Oxidative stress is considered to be an important component of various diseases. A vast number of methods have been developed and used in virtually all diseases to measure the extent and nature of oxidative stress, ranging from oxidation of DNA to proteins, lipids, and free amino acids.

Recent advances

An increased understanding of the biology behind diseases and redox biology has led to more specific and sensitive tools to measure oxidative stress markers, which are very diverse and sometimes very low in abundance.

Critical issues

The literature is very heterogeneous. It is often difficult to draw general conclusions on the significance of oxidative stress biomarkers, as only in a limited proportion of diseases have a range of different biomarkers been u

SUBMITTER: Frijhoff J 

PROVIDER: S-EPMC4657513 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature