Association between treated and untreated obstructive sleep apnea and risk of hypertension.

ABSTRACT:

Context

Systemic hypertension is prevalent among patients with obstructive sleep apnea (OSA). Short-term studies indicate that continuous positive airway pressure (CPAP) therapy reduces blood pressure in patients with hypertension and OSA.

Objective

To determine whether CPAP therapy is associated with a lower risk of incident hypertension.

Design, setting, and participants

A prospective cohort study of 1889 participants without hypertension who were referred to a sleep center in Zaragoza, Spain, for nocturnal polysomnography between January 1, 1994, and December 31, 2000. Incident hypertension was documented at annual follow-up visits up to January 1, 2011. Multivariable models adjusted for confounding factors, including change in body mass index from baseline to cens

SUBMITTER: Marin JM 

PROVIDER: S-EPMC4657563 | biostudies-literature | 2012 May

REPOSITORIES: biostudies-literature