Sarcoma Resection With and Without Vascular Reconstruction: A Matched Case-control Study.

ABSTRACT: To examine the impact of major vascular resection on sarcoma resection outcomes.En bloc resection and reconstruction of involved vessels is being increasingly performed during sarcoma surgery; however, the perioperative and oncologic outcomes of this strategy are not well described.Patients undergoing sarcoma resection with (VASC) and without (NO-VASC) vascular reconstruction were 1:2 matched on anatomic site, histology, grade, size, synchronous metastasis, and primary (vs. repeat) resection. R2 resections were excluded. Endpoints included perioperative morbidity, mortality, local recurrence, and survival.From 2000 to 2014, 50 sarcoma patients underwent VASC resection. These were matched with 100 NO-VASC patients having similar clinicopathologic characteristics. The rates of any complication (74% vs. 44%, P?=?0.002), grade 3 or higher complication (38% vs. 18%, P?=?0.024), and transfusion (66% vs. 33%, P?

SUBMITTER: Poultsides GA 

PROVIDER: S-EPMC4657732 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature