Exploratory Cohort Study of Associations between Serum C - Reactive Protein and Fatigue after Stroke.

ABSTRACT:

Background and aim

Post-stroke fatigue is a common and distressing problem but little is known about its biological mechanisms. This cohort study was to investigate associations between C-reactive protein (CRP) and fatigue after stroke.

Methods

Patients were assessed at one, six and 12 months after their stroke onset, with the Fatigue Assessment Scale, a case definition of post-stroke fatigue, Hospital Anxiety and Depression Scale, and daily step counts. Blood samples were collected at each assessment and the CRP level was determined by a standard CRP immunoassay. Cross-sectional associations between CRP and fatigue at each time point were determined by Pearson correlation coefficient and independent-samples t-test. Whether CRP levels at one month predict fatigue scores at s

SUBMITTER: Wu S 

PROVIDER: S-EPMC4658028 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature