National Trends in Ambulatory Oral Anticoagulant Use.

ABSTRACT:

Background

Four direct oral anticoagulants (DOACs) have been brought to market for the treatment of nonvalvular atrial fibrillation and venous thromboembolism. Many forces, including numerous positive trial results, emerging safety concerns, marketing, and promotion, may shape DOAC adoption by providers. However, relatively little is known regarding their ambulatory utilization compared with warfarin, as well as the degree to which they have decreased under-treatment of atrial fibrillation.

Methods

We used the IMS Health National Disease and Therapeutic Index, a nationally representative audit of outpatient office visits, to estimate the use of warfarin and DOACs between 2009 and 2014.

Results

Overall, visits with anticoagulation use increased from 2.05 (95% confidenc

SUBMITTER: Barnes GD 

PROVIDER: S-EPMC4658248 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature