Hepatitis B virus infection and genotype in asymptomatic people from 10 ethnic groups in Yunnan, China.

ABSTRACT:

Aim

To evaluate the infection and genotype distribution of hepatitis B virus (HBV) in ethnic groups in Yunnan, China.

Methods

Two thousand five hundred and eighty-four asymptomatic local people from 10 ethnic groups were investigated in Yunnan, China. Infection and genotype distribution were evaluated by serological and genetic methods. Genotyping was verified by sequencing. Ethnic genotype distribution was compared by proportion test.

Results

Four types of infection model based on HBV serum markers were identified, and the average HBV infection rate was 5.7% in those asymptomatic local people. The genotype prevalence was 59.6% for B, 21.1% for C and 19.3% BC; subgenotypes Ba, Cs and Ce were identified in this study. Hepatitis B surface antigen-positive rate and the p

SUBMITTER: Shen YY 

PROVIDER: S-EPMC4658612 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature