Dimethylamine as the key intermediate generated in situ from dimethylformamide (DMF) for the synthesis of thioamides.

ABSTRACT: An improved and efficient method for the synthesis of thioamides is presented. For this transformation, dimethylamine as the key intermediate is generated in situ from dimethylformamide (DMF). All the tested substrates produced the desired products with excellent isolated yields.

SUBMITTER: Liu W 

PROVIDER: S-EPMC4660898 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature