CACNA1C risk variant affects facial emotion recognition in healthy individuals.

ABSTRACT: Recognition and correct interpretation of facial emotion is essential for social interaction and communication. Previous studies have shown that impairments in this cognitive domain are common features of several psychiatric disorders. Recent association studies identified CACNA1C as one of the most promising genetic risk factors for psychiatric disorders and previous evidence suggests that the most replicated risk variant in CACNA1C (rs1006737) is affecting emotion recognition and processing. However, studies investigating the influence of rs1006737 on this intermediate phenotype in healthy subjects at the behavioral level are largely missing to date. Here, we applied the "Reading the Mind in the Eyes" test, a facial emotion recognition paradigm in a cohort of 92 healthy individuals to ad

SUBMITTER: Nieratschker V 

PROVIDER: S-EPMC4661469 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature