Genetics of ischaemic stroke in young adults.

ABSTRACT:

Background

Stroke may be a clinical expression of several inherited disorders in humans. Recognition of the underlined genetic disorders causing stroke is important for a correct diagnosis, for genetic counselling and, even if rarely, for a correct therapeutic management. Moreover, the genetics of complex diseases such the stroke, in which multiple genes interact with environmental risk factors to increase risk, has been revolutionized by the Genome-Wide Association Study (GWAS) approach.

Scope of review

Here we review the single-gene causes of ischemic stroke, bringing the reader from the candidate gene method toward the exciting new horizons of genetic technology.

Major conclusions

The aetiological diagnosis of ischemic stroke in young adults is more complex than in

SUBMITTER: Terni E 

PROVIDER: S-EPMC4661509 | biostudies-literature | 2015 Jun

REPOSITORIES: biostudies-literature