Cardiometabolic and vascular risks in young and adolescent girls with Turner syndrome.

ABSTRACT:

Background

Turner syndrome (TS) is the most common chromosomal abnormality in females and is associated with several co-morbidities. It commonly results from X monosomy which is diagnosed on a 30 cell karyotype. Congenital heart disease is a clinical feature in 30% of cases. It is becoming evident that TS patients have an increased risk of cardiovascular and cerebrovascular diseases.

Scope of review

This review provides a detailed overview of the literature surrounding cardiometabolic health in childhood and adolescent TS. In addition, the review also summarises the current data on the impact of growth hormone (GH) therapy on cardiometabolic risk in paediatric TS patients.

Major conclusions

Current epidemiological evidence suggests that young women and girls with TS h

SUBMITTER: Mavinkurve M 

PROVIDER: S-EPMC4661589 | biostudies-literature | 2015 Jun

REPOSITORIES: biostudies-literature