Cognitive training in Parkinson disease: A systematic review and meta-analysis.

ABSTRACT:

Objective

To quantify the effects of cognitive training (CT) on cognitive and behavioral outcome measures in patients with Parkinson disease (PD).

Methods

We systematically searched 5 databases for randomized controlled trials (RCTs) of CT in patients with PD reporting cognitive or behavioral outcomes. Efficacy was measured as standardized mean difference (Hedges g) of post-training change.

Results

Seven studies encompassing 272 patients with Hoehn & Yahr Stages 1-3 were included. The overall effect of CT over and above control conditions was small but statistically significant (7 studies: g = 0.23, 95% confidence interval [CI] 0.014-0.44, p = 0.037). True heterogeneity across studies was low (I(2) = 0%) and there was no evidence of publication bias. Larger effect siz

SUBMITTER: Leung IH 

PROVIDER: S-EPMC4662707 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature