Cross-sectional study of factors influencing sex hormone-binding globulin concentrations in normally cycling premenopausal women.

ABSTRACT:

Objective

To assess the relationship between SHBG and 18 other hormonal and metabolic parameters in well characterized, normally cycling premenopausal women.

Design

Cross-sectional study.

Setting

University general clinical research center.

Subject(s)

A total of 319 young healthy women with ovulatory menstrual cycles.

Intervention(s)

None.

Main outcome measure(s)

Midfollicular serum SHBG concentrations.

Result(s)

In our final linear regression model, SHBG was negatively associated with bioavailable T and positively associated with adiponectin, associations that were independent from other parameters. SHBG was also positively associated with estrone sulfate, but only when taking into account confounding variables. Unexpectedly, there was no

SUBMITTER: Crawford TN 

PROVIDER: S-EPMC4663171 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature