Strain-guided mineralization in the bone-PDL-cementum complex of a rat periodontium.

ABSTRACT:

Objective

The objective of this study was to investigate the effect of mechanical strain by mapping physicochemical properties at periodontal ligament (PDL)-bone and PDL-cementum attachment sites and within the tissues per se.

Design

Accentuated mechanical strain was induced by applying a unidirectional force of 0.06N for 14 days on molars in a rat model. The associated changes in functional space between tooth and bone, mineral formation and resorbing events at the PDL-bone and PDL-cementum attachment sites were identified by using micro-X-ray computed tomography (micro-XCT), atomic force microscopy (AFM), dynamic histomorphometry, Raman microspectroscopy, AFM-based nanoindentation technique, and were correlated with histochemical stains specific to low and high mole

SUBMITTER: Grandfield K 

PROVIDER: S-EPMC4663464 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature