Endovascular vs medical management of acute ischemic stroke.

ABSTRACT:

Objective

To compare the outcomes between endovascular and medical management of acute ischemic stroke in recent randomized controlled trials (RCT).

Methods

A systematic literature review was performed, and multicenter, prospective RCTs published from January 1, 2013, to May 1, 2015, directly comparing endovascular therapy to medical management for patients with acute ischemic stroke were included. Meta-analyses of modified Rankin Scale (mRS) and mortality at 90 days and symptomatic intracranial hemorrhage (sICH) for endovascular therapy and medical management were performed.

Results

Eight multicenter, prospective RCTs (Interventional Management of Stroke [IMS] III, Local Versus Systemic Thrombolysis for Acute Ischemic Stroke [SYNTHESIS] Expansion, Mechanical Retrieva

SUBMITTER: Chen CJ 

PROVIDER: S-EPMC4664128 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature