Investigating Tissue Optical Properties and Texture Descriptors of the Retina in Patients with Multiple Sclerosis.

ABSTRACT:

Purpose

To assess the differences in texture descriptors and optical properties of retinal tissue layers in patients with multiple sclerosis (MS) and to evaluate their usefulness in the detection of neurodegenerative changes using optical coherence tomography (OCT) image segmentation.

Patients and methods

38 patients with MS were examined using Stratus OCT. The raw macular OCT data were exported and processed using OCTRIMA software. The enrolled eyes were divided into two groups, based on the presence of optic neuritis (ON) in the history (MSON+ group, n = 36 and MSON- group, n = 31). Data of 29 eyes of 24 healthy subjects (H) were used as controls. A total of seven intraretinal layers were segmented and thickness as well as optical parameters such as contrast, fractal dimen

SUBMITTER: Varga BE 

PROVIDER: S-EPMC4664388 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature