Biofilm community diversity after exposure to 0·4% stannous fluoride gels.

ABSTRACT:

Aims

To test the effect of 0·4% stannous fluoride (SnF2 ) glycerine-based gels on specific portions of the bacterial community in both a clinical observational study and in vitro multispecies plaque-derived (MSPD) biofilm model.

Methods and results

Potential changes to specific portions of the bacterial community were determined through the Human Oral Microbial Identification Microarray (HOMIM). Both the observational clinical study and the biofilm model showed that short-term use of 0·4% SnF2 gel has little effect on the bacterial community depicted by hierarchical cluster analysis. The amount of plaque accumulation on a subject's teeth, which was measured by plaque index scores, failed to show statistical significant changes over the two baselines or after treatment (P = 0

SUBMITTER: Reilly C 

PROVIDER: S-EPMC4664451 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature