Performance of one-view breast tomosynthesis as a stand-alone breast cancer screening modality: results from the Malmo Breast Tomosynthesis Screening Trial, a population-based study.

ABSTRACT:

Objective

To assess the performance of one-view digital breast tomosynthesis (DBT) in breast cancer screening.

Methods

The Malmö Breast Tomosynthesis Screening Trial is a prospective population-based one-arm study with a planned inclusion of 15000 participants; a random sample of women aged 40-74 years eligible for the screening programme. This is an explorative analysis of the first half of the study population (n = 7500). Participants underwent one-view DBT and two-view digital mammography (DM), with independent double reading and scoring. Primary outcome measures were detection rate, recall rate and positive predictive value (PPV). McNemar's test with 95 % confidence intervals was used.

Results

Breast cancer was found in sixty-eight women. Of these, 46 cases were d

SUBMITTER: Lang K 

PROVIDER: S-EPMC4666282 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature