Ontology highlight
ABSTRACT:
SUBMITTER: Watson GW
PROVIDER: S-EPMC4666544 | biostudies-literature | 2015 Dec
REPOSITORIES: biostudies-literature
EuPA open proteomics 20150810
The phytochemical sulforaphane can induce cell cycle arrest and apoptosis in metastatic prostate cancer cells, though the mechanism of action is not fully known. We conducted a global proteome analysis in LNCaP metastatic prostate cancer cells to characterize how global protein signature responds to sulforaphane. We conducted parallel analyses to evaluate semi-quantitative 1-dimensional versus 2-dimensional liquid chromatography tandem mass spectrometry (LC-MS/MS) and their utility in characteri ...[more]