Ontology highlight
ABSTRACT:
SUBMITTER: Xiong W
PROVIDER: S-EPMC4668354 | biostudies-literature | 2015 Dec
REPOSITORIES: biostudies-literature
Xiong Wenli W Wang Pan P Hu Jianmin J Jia Yali Y Wu Lijie L Chen Xiyang X Liu Quanhong Q Wang Xiaobing X
Scientific reports 20151203
Sonodynamic therapy (SDT) was developed as a promising noninvasive approach. The present study investigated the antitumor effect of a new sensitizer (sinoporphyrin sodium, referred to as DVDMS) combined with multiple ultrasound treatments on sarcoma 180 both in vitro and in vivo. The combined treatment significantly suppressed cell viability, potentiated apoptosis, and markedly inhibited angiogenesis in vivo. In vivo, the tumor weight inhibition ratio reached 89.82% fifteen days after three soni ...[more]