Striatal and Pallidal Activation during Reward Modulated Movement Using a Translational Paradigm.

ABSTRACT: Human neuroimaging studies of reward processing typically involve tasks that engage decision-making processes in the dorsal striatum or focus upon the ventral striatum's response to feedback expectancy. These studies are often compared to the animal literature; however, some animal studies include both feedback and nonfeedback events that activate the dorsal striatum during feedback expectancy. Differences in task parameters, movement complexity, and motoric effort to attain rewards may partly explain ventral and dorsal striatal response differences across species. We, therefore, used a target capture task during functional neuroimaging that was inspired by a study of single cell modulation in the internal globus pallidus during reward-cued, rotational arm movements in nonhuman primates. I

SUBMITTER: Bischoff-Grethe A 

PROVIDER: S-EPMC4668805 | biostudies-literature | 2015 Jul

REPOSITORIES: biostudies-literature