Patient Preferences for Biologicals in Psoriasis: Top Priority of Safety for Cardiovascular Patients.

ABSTRACT: Patients with psoriasis are often affected by comorbidities, which largely influence treatment decisions. Here we performed conjoint analysis to assess the impact of comorbidities on preferences of patients with moderate-to-severe psoriasis for outcome (probability of 50% and 90% improvement, time until response, sustainability of success, probability of mild and severe adverse events (AE), probability of ACR 20 response) and process attributes (treatment location, frequency, duration and delivery method) of biologicals. The influence of comorbidities on Relative Importance Scores (RIS) was determined with analysis of variance and multivariate regression. Among the 200 participants completing the study, 22.5% suffered from psoriatic arthritis, 31.5% from arterial hypertension, 15% from car

SUBMITTER: Schaarschmidt ML 

PROVIDER: S-EPMC4669171 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature