Ontology highlight
ABSTRACT:
SUBMITTER: Lele M
PROVIDER: S-EPMC466960 | biostudies-literature | 2024 Jul
REPOSITORIES: biostudies-literature
Lele Mahima M Kapur Shaunak S Hargett Sarah S Sureshbabu Nivedhitha Malli NM Gaharwar Akhilesh K AK
Science advances 20240717 29
Engineered biomaterials are materials specifically designed to interact with biological systems for biomedical applications. This paper offers the comprehensive analysis of global clinical trial trends involving such materials. We surveyed 834 studies in the ClinicalTrials.gov database and explored biomaterial types, their initiation points, and durations in clinical trials. Predominantly, synthetic and natural polymers, particularly silicone and collagen, are used. Trials, focusing on ophthalmo ...[more]