The course of diaphragm atrophy in ventilated patients assessed with ultrasound: a longitudinal cohort study.

ABSTRACT:

Introduction

Mechanical ventilation and the effect of respiratory muscle unloading on the diaphragm cause ventilator-induced diaphragmatic dysfunction (VIDD). Atrophy of the diaphragmatic muscle is a major part of VIDD, and has a rapid onset in most animal models. We wanted to assess the clinical evolution and risk factors for VIDD in an adult intensive care unit (ICU) by measuring diaphragm thickness using ultrasound.

Method

We performed a single-centre observational cohort study, including 54 mechanically ventilated patients. The right hemidiaphragm was measured daily at the zone of apposition on the midaxillary line.

Results

Mean baseline thickness was 1.9 mm (SD ± 0.4 mm), and mean nadir was 1.3 mm (SD ± 0.4 mm), corresponding with a mean change in thickness of 32

SUBMITTER: Schepens T 

PROVIDER: S-EPMC4671211 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature