Detection of airborne viruses using electro-aerodynamic deposition and a field-effect transistor.

ABSTRACT: We report a technique for the detection of aerosolized viruses. Conventional field-effect-transistor (FET)-based techniques use solution-based processes, thus require antibody binding to the detection region of the FET prior to the supply of the analyte. With the method described here, virus-antibody-bound particles are delivered to the FET during detection; therefore, neither a pre-treatment antibody binding step on the FET channel nor washing process for virus-antibody-binding are necessary. Our method is based on the concept that virus-antibody-bound particles are larger than the virus or antibody alone, and thus have larger charge numbers following aerosol charging. When these particles are charged by negative ions and electro-aerodynamically deposited on a substrate, there exists a lo

SUBMITTER: Park KT 

PROVIDER: S-EPMC4672335 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature