Nitrous oxide-induced slow and delta oscillations.

ABSTRACT:

Objectives

Switching from maintenance of general anesthesia with an ether anesthetic to maintenance with high-dose (concentration >50% and total gas flow rate >4 liters per minute) nitrous oxide is a common practice used to facilitate emergence from general anesthesia. The transition from the ether anesthetic to nitrous oxide is associated with a switch in the putative mechanisms and sites of anesthetic action. We investigated whether there is an electroencephalogram (EEG) marker of this transition.

Methods

We retrospectively studied the ether anesthetic to nitrous oxide transition in 19 patients with EEG monitoring receiving general anesthesia using the ether anesthetic sevoflurane combined with oxygen and air.

Results

Following the transition to nitrous oxide, the a

SUBMITTER: Pavone KJ 

PROVIDER: S-EPMC4675698 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature