A Novel Dynamic Model for Health Economic Analysis of Influenza Vaccination in the Elderly.

ABSTRACT:

Introduction

New vaccines are being developed to improve the efficacy of seasonal influenza immunization in elderly persons aged ≥65 years. These products require clinical and economic evaluation to aid policy decisions.

Methods

To address this need, a two-part model has been developed, which we have applied to examine the potential clinical and economic impact of vaccinating elderly persons with adjuvanted trivalent inactivated influenza vaccine (aTIV) relative to conventional trivalent (TIV) and quadrivalent (QIV) vaccines. We compared outcomes in the US population for (1) aTIV in persons aged ≥65 years and QIV in all other age cohorts; (2) QIV in all cohorts; (3) TIV in all cohorts. Low, average, and high intensity seasons with low, average, and high vaccine match scenari

SUBMITTER: Mullikin M 

PROVIDER: S-EPMC4675767 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature