Chronic Stress During Adolescence Impairs and Improves Learning and Memory in Adulthood.

ABSTRACT: HIGHLIGHTS This study tested the effects of adolescent-stress on adult learning and memory.Adolescent-stressed rats had enhanced reversal learning compared to unstressed rats.Adolescent-stress exposure made working memory more vulnerable to disturbance.Adolescent-stress did not affect adult associative learning or reference memory. Exposure to acute stress can cause a myriad of cognitive impairments, but whether negative experiences continue to hinder individual as they age is not as well understood. We determined how chronic unpredictable stress during adolescence affects multiple learning and memory processes in adulthood. Using male Sprague Dawley rats, we measured learning (both associative and reversal) and memory (both reference and working) starting 110 days after completion of an a

SUBMITTER: Chaby LE 

PROVIDER: S-EPMC4675857 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature