An Intermittent Model for Intracellular Motions of Gold Nanostars by k-Space Scattering Image Correlation.

ABSTRACT: Anisotropic metallic nanoparticles have been devised as powerful potential tools for in vivo imaging, photothermal therapy, and drug delivery thanks to plasmon-enhanced absorption and scattering cross sections, ease in synthesis and functionalization, and controlled cytotoxicity. The rational design of all these applications requires the characterization of the nanoparticles intracellular trafficking pathways. In this work, we exploit live-cell time-lapse confocal reflectance microscopy and image correlation in both direct and reciprocal space to investigate the intracellular transport of branched gold nanostars (GNSs). Different transport mechanisms, spanning from pure Brownian diffusion to (sub-)ballistic superdiffusion, are revealed by temporal and spatio-temporal image correlation spec

SUBMITTER: Bouzin M 

PROVIDER: S-EPMC4675865 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature