Pachygyria Presented as Mania.

ABSTRACT: Psychiatric manifestation of pachygyria, a neuronal migration disorder is rare in literature; rarer if it is bipolar disorder specifically. Here, we report a case of mania and seizure who subsequently diagnosed as pachygyria. Proper literature about pathophysiology is discussed and recently discovered putative genetic role in bipolar disorder explained. This case also emphasis the importance of detailed history taking and imaging investigation even in a pure psychiatric presentation.

SUBMITTER: Chatterjee SS 

PROVIDER: S-EPMC4676216 | biostudies-literature | 2015 Oct-Dec

REPOSITORIES: biostudies-literature