HBF₄-Catalysed Nucleophilic Substitutions of Propargylic Alcohols.

ABSTRACT: The activity of HBF₄ (aqueous solution) as a catalyst in propargylation reactions is presented. Diverse types of nucleophiles were employed in order to form new C-O, C-N and C-C bonds in technical acetone and in air. Good to excellent yields and good chemoselectivities were obtained using low acid loading (typically 1 mol-%) under simple reaction conditions.

SUBMITTER: Barreiro E 

PROVIDER: S-EPMC4676292 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature