Hydrocephalic Parkinsonism: lessons from normal pressure hydrocephalus mimics.

ABSTRACT:

Background

Hydrocephalus is an under-recognized presentation of progressive supranuclear palsy (PSP) and dementia with Lewy bodies (DLB).

Methods

We describe four normal pressure hydrocephalus (NPH)-like presentations of pathology-proven PSP (n = 3) and DLB (n = 1) and review the literature on the hydrocephalic presentation of these atypical parkinsonisms.

Results

Despite the presence of ventriculomegaly disproportionate to the extent of parenchymal atrophy, all patients demonstrated early postural impairment and/or oculomotor abnormalities that encouraged a diagnostic revision. Hallucinations were the only early atypical manifestation of the hydrocephalic DLB presentation.

Conclusions

Early postural impairment, falls, oculomotor impairment, and/or hallucinatio

SUBMITTER: Starr BW 

PROVIDER: S-EPMC4677733 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature