Generation and Evaluation of a Cortical Area Parcellation from Resting-State Correlations.

ABSTRACT: The cortical surface is organized into a large number of cortical areas; however, these areas have not been comprehensively mapped in the human. Abrupt transitions in resting-state functional connectivity (RSFC) patterns can noninvasively identify locations of putative borders between cortical areas (RSFC-boundary mapping; Cohen et al. 2008). Here we describe a technique for using RSFC-boundary maps to define parcels that represent putative cortical areas. These parcels had highly homogenous RSFC patterns, indicating that they contained one unique RSFC signal; furthermore, the parcels were much more homogenous than a null model matched for parcel size when tested in two separate datasets. Several alternative parcellation schemes were tested this way, and no other parcellation was as homoge

SUBMITTER: Gordon EM 

PROVIDER: S-EPMC4677978 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature