Resting-State Network Complexity and Magnitude Are Reduced in Prematurely Born Infants.

ABSTRACT: Premature birth is associated with high rates of motor and cognitive disability. Investigations have described resting-state functional magnetic resonance imaging (rs-fMRI) correlates of prematurity in older children, but comparable data in the neonatal period remain scarce. We studied 25 term-born control infants within the first week of life and 25 very preterm infants (born at gestational ages ranging from 23 to 29 weeks) without evident structural injury at term equivalent postmenstrual age. Conventional resting-state network (RSN) mapping revealed only modest differences between the term and prematurely born infants, in accordance with previous work. However, clear group differences were observed in quantitative analyses based on correlation and covariance matrices representing the fu

SUBMITTER: Smyser CD 

PROVIDER: S-EPMC4677980 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature