Circulating Betatrophin in Patients with Type 2 Diabetes: A Meta-Analysis.

ABSTRACT:

Objective

To investigate the association between circulating betatrophin level and type 2 diabetes mellitus (T2DM) in human.

Methods

A comprehensive literature search was performed in PubMed and Embase databases to identify eligible studies assessing the circulating levels of betatrophin in both T2DM patients and nondiabetic adults.

Results

A total of nine eligible studies with twelve comparisons were included for the final meta-analysis. Circulating betatrophin levels in T2DM patients were higher than those in the nondiabetic controls (random-effect SMD 0.53; 95% CI 0.13 to 0.94; P = 0.010). In the subgroup of nonobese population but not the obese population, the overall betatrophin level in T2DM patients was much higher than that in the nondiabetic controls (nonobes

SUBMITTER: Li S 

PROVIDER: S-EPMC4678092 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature