Psychometric modeling of abuse and dependence symptoms across six illicit substances indicates novel dimensions of misuse.

ABSTRACT:

Aims

This study explored the factor structure of DSM III-R/IV symptoms for substance abuse and dependence across six illicit substance categories in a population-based sample of males.

Method

DSM III-R/IV drug abuse and dependence symptoms for cannabis, sedatives, stimulants, cocaine, opioids and hallucinogens from 4179 males born 1940-1970 from the population-based Virginia Adult Twin Study of Psychiatric and Substance Use Disorders were analyzed. Confirmatory factor analyses tested specific hypotheses regarding the latent structure of substance misuse for a comprehensive battery of 13 misuse symptoms measured across six illicit substance categories (78 items).

Results

Among the models fit, the latent structure of substance misuse was best represented by a combinatio

SUBMITTER: Clark SL 

PROVIDER: S-EPMC4679450 | biostudies-literature | 2016 Feb

REPOSITORIES: biostudies-literature