Fiber-optic Monitoring of Spinal Cord Hemodynamics in Experimental Aortic Occlusion.

ABSTRACT:

Background

Spinal cord ischemia occurs frequently during thoracic aneurysm repair. Current methods based on electrophysiology techniques to detect ischemia are indirect, non-specific, and temporally slow. In this article, the authors report the testing of a spinal cord blood flow and oxygenation monitor, based on diffuse correlation and optical spectroscopies, during aortic occlusion in a sheep model.

Methods

Testing was carried out in 16 Dorset sheep. Sensitivity in detecting spinal cord blood flow and oxygenation changes during aortic occlusion, pharmacologically induced hypotension and hypertension, and physiologically induced hypoxia/hypercarbia was assessed. Accuracy of the diffuse correlation spectroscopy measurements was determined via comparison with microsphere bloo

SUBMITTER: Kogler AS 

PROVIDER: S-EPMC4679520 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature