Management of Chronic Kidney Disease: The Relationship Between Serum Uric Acid and Development of Nephropathy.

ABSTRACT:

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Chronic kidney disease (CKD) is increasingly recognized as a global health problem, and new and effective strategies are needed for the management of this condition. Recently, there has been renewed interest in the relationship between serum uric acid (SUA) levels and CKD, and several recent trials have demonstrated a possible link between SUA and the development and/or progression of CKD in patients with and without diabetes. The identification of key urate transporters such as urate transporter 1 and glucose transporter 9 has provided not only insights into the pathophysiology of hyperuricemia, but also possible links to other processes, such as glucose homeostasis. The renewed interest in the role of SUA in CKD has coincided with the development of sodium glucose co-t

SUBMITTER: Mende C 

PROVIDER: S-EPMC4679778 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature