Characteristics Relating to Adherence and Persistence to Basal Insulin Regimens Among Elderly Insulin-Naive Patients with Type 2 Diabetes: Pre-Filled Pens versus Vials/Syringes.

ABSTRACT:

Introduction

Previous studies have found higher rates of adherence in patients with type 2 diabetes mellitus (T2DM) using insulin pens compared to vial and syringe administration; however, little evidence is available to support this observation in elderly patients.

Methods

This was a retrospective claims database analysis of a predominantly elderly Medicare Advantage with Prescription Drug (MAPD) insurance population consisting of 3172 insulin-naïve patients with T2DM who initiated basal insulin using pre-filled pens or vial and syringe ('vial'). The index date was defined by the first pharmacy claim for basal insulin. Adherence, measured as proportion of days covered (PDC) and medication possession ratio (MPR), and persistence were evaluated in a 12-month follow-up period

SUBMITTER: Slabaugh SL 

PROVIDER: S-EPMC4679781 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature