Is higher serum cholesterol associated with altered tendon structure or tendon pain? A systematic review.

ABSTRACT:

Background

Tendon pain occurs in individuals with extreme cholesterol levels (familial hypercholesterolaemia). It is unclear whether the association with tendon pain is strong with less extreme elevations of cholesterol.

Objective

To determine whether lipid levels are associated with abnormal tendon structure or the presence of tendon pain.

Methods

We conducted a systematic review and meta-analysis. Relevant articles were found through an electronic search of 6 medical databases-MEDLINE, Cochrane, AMED, EMBASE, Web of Science and Scopus. We included all case-control or cross-sectional studies with data describing (1) lipid levels or use of lipid-lowering drugs and (2) tendon structure or tendon pain.

Results

17 studies (2612 participants) were eligible for incl

SUBMITTER: Tilley BJ 

PROVIDER: S-EPMC4680137 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature