Relationship between hWAPL polymorphisms and cervical cancer susceptibility.

ABSTRACT:

Purpose

To analyze the correlation of the polymorphisms of human wing-apart like (hWAPL) gene (rs7083506 and rs11202058) with the susceptibility to cervical cancer. Besides, the relationship of haplotypes between the polymorphisms with cervical cancer susceptibility was analyzed.

Methods

Taqman probe genotyping method was adopted to detect the genotype distribution of hWAPL rs7083506 and rs11202058 polymorphisms in 117 cervical cancer patients and 128 healthy controls. Linkage disequilibrium and haplotypes were analyzed by Haploview software. χ(2) test was utilized to analyze the differences of genotype, allele and haplotype frequencies between the case and control groups.

Results

Correlation analysis of hWAPL rs7083506 and rs11202058 polymorphisms with cervical cance

SUBMITTER: Li L 

PROVIDER: S-EPMC4680553 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature