Emergence of Rotavirus G12P[8] in St. Louis During the 2012-2013 Rotavirus Season.

ABSTRACT:

Background

We observed an increase in the number of rotavirus cases in the St. Louis area during the 2012-2013 rotavirus season compared with recent seasons. We aimed to determine whether the rotavirus cases during the 2012-2013 rotavirus season were of types not included in licensed vaccines.

Methods

Microbiology laboratories of 3 children's hospitals in St. Louis provided samples that were positive using rapid antigen tests from 2010 to 2013. The majority of samples were from St. Louis Children's Hospital. We determined rotavirus genotypes by polymerase chain reaction tests and further characterized a subset of viruses by genome sequencing and comparative sequence analysis.

Results

Eighty-six percent (24 of 28) of typed viruses analyzed from the 2012-2013 rotavirus

SUBMITTER: Wylie KM 

PROVIDER: S-EPMC4681384 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature