Network community structure alterations in adult schizophrenia: identification and localization of alterations.

ABSTRACT: A growing body of literature suggests functional connectivity alterations in schizophrenia. While findings have been mixed, evidence points towards a complex pattern of hyper-connectivity and hypo-connectivity. This altered connectivity can be represented and analyzed using the mathematical frameworks provided by graph and information theory to represent functional connectivity data as graphs comprised of nodes and edges linking the nodes. One analytic technique in this framework is the determination and analysis of network community structure, which is the grouping of nodes into linked communities or modules. This data-driven technique finds a best-fit structure such that nodes in a given community have greater connectivity with nodes in their community than with nodes in other communitie

SUBMITTER: Lerman-Sinkoff DB 

PROVIDER: S-EPMC4683428 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature