Wireless fluorescence capsule for endoscopy using single photon-based detection.

ABSTRACT: Fluorescence Imaging (FI) is a powerful technique in biological science and clinical medicine. Current FI devices that are used either for in-vivo or in-vitro studies are expensive, bulky and consume substantial power, confining the technique to laboratories and hospital examination rooms. Here we present a miniaturised wireless fluorescence endoscope capsule with low power consumption that will pave the way for future FI systems and applications. With enhanced sensitivity compared to existing technology we have demonstrated that the capsule can be successfully used to image tissue autofluorescence and targeted fluorescence via fluorophore labelling of tissues. The capsule incorporates a state-of-the-art complementary metal oxide semiconductor single photon avalanche detector imaging array

SUBMITTER: Al-Rawhani MA 

PROVIDER: S-EPMC4683524 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature