Fluorescence Phenomena in Nerve-Labeling Styryl-Type Dyes.

ABSTRACT: Several classes of diversely substituted styryl type dyes have been synthesized with the goal of extending their expected fluorescent properties as much towards red as possible given the constraint that they maintain drug-like properties and retain high affinity binding to their biological target. We report on the synthesis, optical properties of a series of styryl dyes ( d1-d14 ), and the anomalous photophysical behavior of several of these Donor-Acceptor pairs separated by long conjugated π-systems ( d7-d10 ). We further describe an unusual dual emission behavior with two distinct ground state conformers which could be individually excited to locally excited (LE) and twisted intramolecular charge transfer (TICT) excited state in push-pull dye systems ( d

SUBMITTER: Siclovan TM 

PROVIDER: S-EPMC4683607 | biostudies-literature | 2016 Feb

REPOSITORIES: biostudies-literature