Increased norovirus activity was associated with a novel norovirus GII.17 variant in Beijing, China during winter 2014-2015.

ABSTRACT:

Background

Norovirus (NoV) is a leading cause of sporadic cases and outbreaks of acute gastroenteritis (AGE). Increased NoV activity was observed in Beijing, China during winter 2014-2015; therefore, we examined the epidemiological patterns and genetic characteristics of NoV in the sporadic cases and outbreaks.

Methods

The weekly number of infectious diarrhea cases reported by all hospitals in Beijing was analyzed through the China information system for disease control and prevention. Fecal specimens were collected from the outbreaks and outpatients with AGE, and GI and GII NoVs were detected using real time reverse transcription polymerase chain reaction. The partial capsid genes and RNA-dependent RNA polymerase (RdRp) genes of NoV were both amplified and sequenced, and ge

SUBMITTER: Gao Z 

PROVIDER: S-EPMC4683961 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature