Neuroanatomical Correlates of Recognizing Face Expressions in Mild Stages of Alzheimer's Disease.

ABSTRACT: Early Alzheimer's disease can involve social disinvestment, possibly as a consequence of impairment of nonverbal communication skills. This study explores whether patients with Alzheimer's disease at the mild cognitive impairment or mild dementia stage have impaired recognition of emotions in facial expressions, and describes neuroanatomical correlates of emotion processing impairment. As part of the ongoing PACO study (personality, Alzheimer's disease and behaviour), 39 patients with Alzheimer's disease at the mild cognitive impairment or mild dementia stage and 39 matched controls completed tests involving discrimination of four basic emotions-happiness, fear, anger, and disgust-on photographs of faces. In patients, automatic volumetry of 83 brain regions was performed on structural magn

SUBMITTER: Sapey-Triomphe LA 

PROVIDER: S-EPMC4684414 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature